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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-376c
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM)
Methods microarray, qPCR
Expression pattern down-regulated
Functional description Among the miRNAs that were downregulated in both cell lines, the deregulation of miR-376a and miR-376c has been shown to contribute to IGF1R overexpression and to promote melanomagenesis and metastasis.
PubMed ID 24675509
Year 2014
Title Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines.
Drug-related ncRNA NO

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