ncRNA name | hsa-miR-376c |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM) |
Methods | microarray, qPCR |
Expression pattern | down-regulated |
Functional description | Among the miRNAs that were downregulated in both cell lines, the deregulation of miR-376a and miR-376c has been shown to contribute to IGF1R overexpression and to promote melanomagenesis and metastasis. |
PubMed ID | 24675509 |
Year | 2014 |
Title | Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines. |
Drug-related ncRNA | NO |
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